The PowerLab C Rodent Langendorff Foundation System is designed to perfuse an isolated mouse or rat heart, either in constant perfusion pressure or constant perfusion flow. Included is the high-quality, modular, yet compact ADInstruments Rodent Langendorff Apparatus, which provides flexibility for configuring various isolated heart experimental solutions. Additionally, the system is also supplied with LabChart Lightning software, flexible PowerLab C data acquisition, and hardware for measuring perfusion pressure and temperature. Further tailored parameters can be made by additionally purchasing from a range of compatible isolated heart kits, which includes measurements of left ventricular developed pressure, heart rate and biopotentials.